I’ll start by saying, I am by no means a great designer, and most of my experience is in the very functional engineering realm. However, I’ve had an idea for multi-material 3D printed shoes. Prior to the U1, it wasn’t very feasible. My idea is to use PETG/ASA to stiffen the soles, while maintaining some flexibility. The shoes would still be made from a mix of TPU 85/95A. Maybe even make replaceable PEBA tread. If I’m way off of possibility, please let me know and why. Just thought it would be an interesting project with a lot of possibilities. Let me know if you’ve seen someone already do this, because I don’t much care to try and recreate the wheel.
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Looking forward to more on this project 
My second print on the U1 was ASA and PLA, including two spools of metal filled PLA. I got some flack on Discord for trying it, even though it came out way better than I expected. I’ve since stuck to this forum because the Community here is awesome!
Anyway, my point is try it! Tag me when you have a test print and I’ll help out as much as my time allows.
I think this is definitely feasible and am curious to see what you come up with! I have no experience using TPU with ASA; however, I did print some 85A TPU which printed amazingly well after adjusting the extruder gear tension.
I can also recommend using nylon as a rigid material to combine with TPU, as these bond very well together especially when printing nylon at high temperatures (285°C)
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