I believe you are still under extruded. This is visible on your first few layers and infill.
Calibrate your e-steps again, mine was at 250 steps per mm on my single extruder, your 225 seems like factory setting for me.
Additionally to this i would suggest to lower your live z-offset, your first layer is too high and the extrusions do not join together.
If this is not causing the (whole) issue, is your filament pulled easily?
If the force of pulling is too high while extruding, this would cause the same issue like inconsistent extrusion and holes in the print.
Clogging would cause similar behaviour but exchanging the hotend or nozzle should be the last resort in this case.
By the way, what speeds and retraction settings do you use?